Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Hepacivirus C |
Protein Variants | Comment | Organism |
---|---|---|
P495A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
P496A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
R32A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
R32K | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
R32S | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
R503A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation completely ablates RNA replication in the cell | Hepacivirus C |
S29A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation decreases RNA replication in the cell | Hepacivirus C |
V499A | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation increases RNA replication in cells | Hepacivirus C |
V499G | mutation in the rGTP-specific binding site does not cause a decrease in RNA-dependent RNA polymerase in vitro. Mutation completely ablates RNA replication in the cell | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Hepacivirus C |
Synonyms | Comment | Organism |
---|---|---|
HCV NS5B | - |
Hepacivirus C |
RDRP | - |
Hepacivirus C |
RNA-dependent RNA polymerase | - |
Hepacivirus C |