Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.48 extracted from

  • Bressanelli, S.; Tomei, L.; Roussel, A.; Incitti, I.; Vitale, R.L.; Mathieu, M.; De Francesco, R.; Rey, F.A.
    Crystal structure of the RNA-dependent RNA polymerase of Hepatitis C virus (1999), Proc. Natl. Acad. Sci. USA, 96, 13034-13039.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine the enzyme is a key target for developing specific antiviral therapy Hepacivirus C

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C P26663
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
Hepacivirus C diphosphate + RNAn+1
-
?