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Literature summary for 2.7.7.42 extracted from
- Reconstitution of Escherichia coli glutamine synthetase adenylyltransferase from N-terminal and C-terminal fragments of the enzyme (2009), Biochemistry, 48, 415-423.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| glutamine | adenylyltransferase activity | Escherichia coli |  |
| PII signal transduction protein | adenylyltransferase activity | Escherichia coli | |
| PII-UMP | adenylyl-removing activity | Escherichia coli | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glutamine | adenylyl-removing activity | Escherichia coli | |
| PII signal transduction protein | adenylyl-removing activity | Escherichia coli | |
| PII-UMP | adenylyltransferase activity | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + glutamine synthetase | Escherichia coli | - |
adenyl-[glutamine synthetase] + phosphate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + glutamine synthetase | - |
Escherichia coli | adenyl-[glutamine synthetase] + phosphate | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutamine synthetase adenylyltransferase | - |
Escherichia coli |
| GS ATase | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Escherichia coli | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the adenylyltransferase and its substrate glutamine synthetase are part of a signal transduction system that includes two additional proteins, uridylyltransferase/uridylyl-removing enzyme and the PII protein | Escherichia coli |
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