Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral protein of the inner membrane | Escherichia coli | 16020 | - |
mitochondrion | enzyme is associated with both, the mitochondria and the endoplasmic reticulum | Saccharomyces cerevisiae | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | stimulates | Escherichia coli | |
K+ | stimulates | Saccharomyces cerevisiae | |
Mg2+ | required | Escherichia coli | |
Mg2+ | the only divalent cation that supports activity | Saccharomyces cerevisiae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
114000 | - |
radiation inactivation | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + phosphatidate | Escherichia coli | the enzyme is involved in the regulation of phospholipid metabolism | diphosphate + CDPdiacylglycerol | - |
? | |
CTP + phosphatidate | Saccharomyces cerevisiae | the enzyme is involved in the regulation of phospholipid metabolism | diphosphate + CDPdiacylglycerol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
CTP + phosphatidate = diphosphate + CDP-diacylglycerol | sequential ordered reaction mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + phosphatidate | - |
Saccharomyces cerevisiae | diphosphate + CDPdiacylglycerol | - |
? | |
CTP + phosphatidate | strong preference for phosphatidic acid with 16-carbon and 18-carbon length fatty acids and at least one unsaturated fatty acid | Escherichia coli | diphosphate + CDPdiacylglycerol | - |
? | |
CTP + phosphatidate | the enzyme is involved in the regulation of phospholipid metabolism | Escherichia coli | diphosphate + CDPdiacylglycerol | - |
? | |
CTP + phosphatidate | the enzyme is involved in the regulation of phospholipid metabolism | Saccharomyces cerevisiae | diphosphate + CDPdiacylglycerol | - |
? | |
dCTP + phosphatidate | - |
Saccharomyces cerevisiae | diphosphate + dCDPdiacylglycerol | - |
? | |
dCTP + phosphatidate | reaction at the same rate as CTP | Escherichia coli | diphosphate + dCDPdiacylglycerol | - |
? |