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Literature summary for 2.7.7.41 extracted from

  • Petzold, G.L.; Agranoff, B.W.
    The biosynthesis of cytidine diphosphate diglyceride by embryonic chick brain (1967), J. Biol. Chem., 242, 1187-1191.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
deoxycholate partial inhibition Gallus gallus
Mg2+ in presence of Mn2+ Gallus gallus
palmitoyl-CoA inhibits incorporation of CTP into CDP-diglyceride in presence or absence of added phosphatidic acid Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
particle-bound
-
Gallus gallus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ maximal activity at 18 mM Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain embryonic Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + phosphatidate didecanoyl phosphatidic acid is the most active of the synthetic phosphatidic acids tested, lysophosphatidic acid is a poor substrate Gallus gallus diphosphate + CDPdiacylglycerol
-
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pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Gallus gallus

pH Range

pH Minimum pH Maximum Comment Organism
5.8 7.6 pH 5.8: 60% of maximal activity, pH 7.6: about 55% of maximal activity Gallus gallus