Any feedback?
Literature summary for 2.7.7.41 extracted from
- Biosynthesis of cytidine diphosphate-diglyceride by a particulate fraction from Micrococcus cerificans (1968), J. Biol. Chem., 243, 5074-5080.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Cutsum | enhances activity | Micrococcus cerificans | |
| non-ionic detergent | absolute requirement | Micrococcus cerificans | |
| Triton X-100 | stimulates | Micrococcus cerificans |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| hydrazine | - |
Micrococcus cerificans | |
| sodium deoxycholate | - |
Micrococcus cerificans | |
| sodium lauryl sulfate | - |
Micrococcus cerificans | |
| Tween 20 | - |
Micrococcus cerificans | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| K+ | absolute requirement for | Micrococcus cerificans | |
| Mg2+ | stimulates, 3times more active than Mn2+, optimal activity at 10 mM | Micrococcus cerificans | |
| Mn2+ | stimulates | Micrococcus cerificans | |
| NH4+ | only about half of the activity observed with K+ | Micrococcus cerificans | |
| Rb+ | only about half of the activity observed with K+ | Micrococcus cerificans | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + phosphatidate | Micrococcus cerificans | enzyme is involved in synthesis of CDP-diglyceride, which plays a primary role in bacterial biosyntheses of essential phosphoglycerides | diphosphate + CDPdiacylglycerol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Micrococcus cerificans | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Micrococcus cerificans |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.1333 | - |
- |
Micrococcus cerificans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + phosphatidate | highly specific for CTP | Micrococcus cerificans | diphosphate + CDPdiacylglycerol | - |
? | |
| CTP + phosphatidate | enzyme is involved in synthesis of CDP-diglyceride, which plays a primary role in bacterial biosyntheses of essential phosphoglycerides | Micrococcus cerificans | diphosphate + CDPdiacylglycerol | - |
? | |
| dCTP + phosphatidate | 50% of the activity with CTP | Micrococcus cerificans | diphosphate + dCDPdiacylglycerol | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 45 | - |
- |
Micrococcus cerificans |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
30 min, irreversible inactivation | Micrococcus cerificans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Micrococcus cerificans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9.3 | pH 6.0: about 45% of maximal activity, pH 9.3: about 40% of maximal activity | Micrococcus cerificans |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
