Literature summary for 2.7.7.38 extracted from

Kondo, K.; Doi, H.; Adachi, H.; Nishimura, Y.
Synergistic effect of CMP/KDO synthase inhibitors with antimicrobial agents on inhibition of production and release of vero toxin by enterohaemorrhagic Escherichia coli O157:H7 (2004), Bioorg. Med. Chem. Lett., 14, 467-470.

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Application

Application	Comment	Organism
medicine	kanamycin and fosfomycin show no inhibitory effect on the production and release of Vero toxins by Escherichia coli O157, both kanamycin and fosfomycin show the remarkable inhibition of Vero toxin 2 release through synergistic collaboration with CMP:KDO synthase inhibitor (1R,4S,5R)-3-[2-[(S)-1-((S)-1-carboxy-ethylcarbamoyl)-ethylamino]-ethyl]-4,5-dihydroxy-cyclohexanecarboxylic acid	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
(1R,4S,5R)-3-[2-[(S)-1-((S)-1-carboxy-ethylcarbamoyl)-ethylamino]-ethyl]-4,5-dihydroxy-cyclohexanecarboxylic acid	-	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Synonyms

Synonyms	Comment	Organism
CMP/KDO synthase	-	Escherichia coli
CMP:KDO synthase	-	Escherichia coli

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Release 2023.1 (January 2023)