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Literature summary for 2.7.7.31 extracted from

  • Deibel, M.R.; Coleman, M.S.
    Purification of a high molecular weight human terminal deoxynucleotidyl transferase (1979), J. Biol. Chem., 254, 8634-8649.
    View publication on PubMed
Search for more literature for 2.7.7.31

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ divalent metal required Homo sapiens
Mg2+ Mg2+ is more effective than Mn2+ Homo sapiens
Mn2+ Mg2+ or Mn2+ required Homo sapiens
Mn2+ Mg2+ is more effective than Mn2+ Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information may contain a small amount of carbohydrate Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblast from leukemic patients Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn primer required Homo sapiens diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn reaction is not template directed Homo sapiens diphosphate + DNAn+1
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 62000, SDS-PAGE Homo sapiens