Protein Variants | Comment | Organism |
---|---|---|
D184A | the ratio of turnover number to Km-value (for GTP) is 1.02fold higher than the wild-type ratio | Homo sapiens |
D299A | the ratio of turnover number to Km-value (for GTP) is 1.04fold higher than the wild-type ratio | Homo sapiens |
D427A | the ratio of turnover number to Km-value (for GTP) is 1.06fold lower than the wild-type ratio | Homo sapiens |
D77A | the ratio of turnover number to Km-value (for GTP) is 16600fold lower than the wild-type ratio | Homo sapiens |
E289A | the ratio of turnover number to Km-value (for GTP) is 1.1fold lower than the wild-type ratio | Homo sapiens |
E297A | the ratio of turnover number to Km-value (for GTP) is 19.5fold lower than the wild-type ratio | Homo sapiens |
E297A/E432A | the ratio of turnover number to Km-value (for GTP) is 24900fold lower than the wild-type ratio | Homo sapiens |
E432A | the ratio of turnover number to Km-value (for GTP) is 113fold lower than the wild-type ratio | Homo sapiens |
E566A | the ratio of turnover number to Km-value (for GTP) is 1.06fold higher than the wild-type ratio | Homo sapiens |
E574A | the ratio of turnover number to Km-value (for GTP) is 1.05fold lower than the wild-type ratio | Homo sapiens |
K478A | the ratio of turnover number to Km-value (for GTP) is 1.13fold lower than the wild-type ratio | Homo sapiens |
K479A | the ratio of turnover number to Km-value (for GTP) is 1.15fold lower than the wild-type ratio | Homo sapiens |
K482A | the ratio of turnover number to Km-value (for GTP) is 166fold lower than the wild-type ratio | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0491 | - |
GTP | pH 7.0, 37°C, mutant enzyme D427A | Homo sapiens | |
0.0496 | - |
GTP | pH 7.0, 37°C, mutant enzyme E566A | Homo sapiens | |
0.0501 | - |
GTP | pH 7.0, 37°C, mutant enzyme D299A | Homo sapiens | |
0.0502 | - |
GTP | pH 7.0, 37°C, wild-type enzyme | Homo sapiens | |
0.0506 | - |
GTP | pH 7.0, 37°C, mutant enzyme E574A | Homo sapiens | |
0.0511 | - |
GTP | pH 7.0, 37°C, mutant enzyme K479A | Homo sapiens | |
0.0512 | - |
GTP | pH 7.0, 37°C, mutant enzyme D184A | Homo sapiens | |
0.0522 | - |
GTP | pH 7.0, 37°C, mutant enzyme K478A | Homo sapiens | |
0.0537 | - |
GTP | pH 7.0, 37°C, mutant enzyme E289A | Homo sapiens | |
0.0805 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A | Homo sapiens | |
0.127 | - |
GTP | pH 7.0, 37°C, mutant enzyme E432A | Homo sapiens | |
0.289 | - |
GTP | pH 7.0, 37°C, mutant enzyme D77A | Homo sapiens | |
0.422 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A/E432A | Homo sapiens | |
0.633 | - |
GTP | pH 7.0, 37°C, mutant enzyme K482A | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + L-fucose 1-phosphate | - |
Homo sapiens | diphosphate + GDP-L-fucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GFPP | - |
Homo sapiens |
GTP fucose pyrophosphorylase | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
GTP | pH 7.0, 37°C, mutant enzyme D77A | Homo sapiens | |
0.001 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A/E432A | Homo sapiens | |
0.05 | - |
GTP | pH 7.0, 37°C, mutant enzyme E432A | Homo sapiens | |
0.19 | - |
GTP | pH 7.0, 37°C, mutant enzyme K482A | Homo sapiens | |
0.2 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A | Homo sapiens | |
2.2 | - |
GTP | pH 7.0, 37°C, mutant enzyme K479A | Homo sapiens | |
2.3 | - |
GTP | pH 7.0, 37°C, mutant enzyme K478A | Homo sapiens | |
2.4 | - |
GTP | pH 7.0, 37°C, mutant enzyme E289A | Homo sapiens | |
2.4 | - |
GTP | pH 7.0, 37°C, mutant enzyme E574A | Homo sapiens | |
2.5 | - |
GTP | pH 7.0, 37°C, wild-type enzyme | Homo sapiens | |
2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D184A | Homo sapiens | |
2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D299A | Homo sapiens | |
2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D427A | Homo sapiens | |
2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme E566A | Homo sapiens |