Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Cryptococcus neoformans | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP + alpha-D-mannose 1-phosphate | Cryptococcus neoformans | - |
phosphate + GDP-mannose | - |
? | |
additional information | Cryptococcus neoformans | GDP-mannose, the mannose donor, required for the main cryptococcal virulence factor, a polysaccharide capsule that surrounds the cell, is produced in the cytosol by the sequential actions of phosphomannose isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase. Cryptococcus neoformans is a fungal pathogen that is responsible for life-threatening disease, particularly in the context of compromised immunity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cryptococcus neoformans | - |
serotype D strains JEC21 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP + alpha-D-mannose 1-phosphate | - |
Cryptococcus neoformans | phosphate + GDP-mannose | - |
? | |
additional information | GDP-mannose, the mannose donor, required for the main cryptococcal virulence factor, a polysaccharide capsule that surrounds the cell, is produced in the cytosol by the sequential actions of phosphomannose isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase. Cryptococcus neoformans is a fungal pathogen that is responsible for life-threatening disease, particularly in the context of compromised immunity | Cryptococcus neoformans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GDP-D-mannose pyrophosphorylase | - |
Cryptococcus neoformans |