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Literature summary for 2.7.7.15 extracted from

  • Kacher, Y.; Golan, A.; Pewzner-Jung, Y.; Futerman, A.H.
    Changes in macrophage morphology in a Gaucher disease model are dependent on CTP:phosphocholine cytidylyltransferase alpha (2007), Blood Cells Mol. Dis., 39, 124-129.
    View publication on PubMed
Search for more literature for 2.7.7.15

Activating Compound

Activating Compound Comment Organism Structure
conduritol-B-epoxide treatment of macrophages with 0.5 mM conduritol-B-epoxide results in elevated activity of CCT Mus musculus
conduritol-B-epoxide treatment of macrophages with 0.5 mM conduritol-B-epoxide results in elevated activity of CCT Homo sapiens

Application

Application Comment Organism
medicine possible role for macrophage CCTalpha in Gaucher disease pathology Mus musculus
medicine possible role for macrophage CCTalpha in Gaucher disease pathology Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage CCTalpha is the major CCT isoform in macrophages Mus musculus
-
macrophage CCTalpha is the major CCT isoform in macrophages Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + choline phosphate
-
 Mus musculus diphosphate + CDP-choline
-
 ?
CTP + choline phosphate
-
 Homo sapiens diphosphate + CDP-choline
-
 ?

Synonyms

Synonyms Comment Organism
CCTalpha isozyme Mus musculus
CCTalpha isozyme Homo sapiens
CTP:phosphocholine cytidylyltransferase alpha
-
 Mus musculus
CTP:phosphocholine cytidylyltransferase alpha
-
 Homo sapiens