Literature summary for 2.7.7.15 extracted from

Choy, P.C.; Vance, D.E.
Lipid requirements for activation of CTP:phosphocholine cytidylyltransferase from rat liver (1978), J. Biol. Chem., 253, 5163-5167.

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Inhibitors

Inhibitors	Comment	Organism	Structure
lysophosphatidylcholine	99% inhibition of L-form, only partial inhibition of H-form	Rattus norvegicus
Sn-3-Lysophosphatidylcholine	-	Rattus norvegicus
Triton X-100	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.00296	-	L-form	Rattus norvegicus
0.025	-	H-form	Rattus norvegicus

Storage Stability

Storage Stability	Organism
4°C, increase of activity in fresh cytosol obtained by storage is due to an increase of lysophosphatidylethanolamine and a decrease in phosphatidylethanolamine	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CTP + choline phosphate	-	Rattus norvegicus	diphosphate + CDPcholine	-	?

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Release 2023.1 (January 2023)