Literature summary for 2.7.7.12 extracted from

Ellis, G.; Goldberg, D.M.
Galactose-1-phosphate uridylytransferase. UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase, EC 2.7.7.12 (1983), Methods Enzym. Anal. , 3rd. Ed. (Bergmeyer, H. U. , ed. ), 3, 560-571.

No PubMed abstract available

Search for more literature for 2.7.7.12

General Stability

General Stability	Organism
sulfhydryl reagents restore activity of partially denatured enzyme and protect against inactivation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
ADP	erythrocytes	Homo sapiens
alpha-D-glucose 1-phosphate	erythrocytes	Homo sapiens
ATP	erythrocytes	Homo sapiens
Cl-	-	Bos taurus
Cl-	-	Homo sapiens
D-glucose 6-phosphate	erythrocytes	Homo sapiens
diethyldicarbonate	erythrocytes	Homo sapiens
iodoacetate	erythrocytes	Homo sapiens
PCMB	erythrocytes	Homo sapiens
UDP	-	Bos taurus
UDP-glucose	product inhibition	Bos taurus
UDP-glucose	product inhibition	Homo sapiens
UMP	-	Bos taurus
UTP	-	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	calf	-
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-
leukocyte	-	Homo sapiens	-
liver	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-glucose + alpha-D-galactose 1-phosphate	-	Homo sapiens	alpha-D-glucose 1-phosphate + UDP-galactose	-	r
UDP-glucose + alpha-D-galactose 1-phosphate	-	Bos taurus	alpha-D-glucose 1-phosphate + UDP-galactose	-	r

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.7	-	erythrocytes	Homo sapiens

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Release 2023.1 (January 2023)