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Literature summary for 2.7.7.106 extracted from

  • Braga, D.; Last, D.; Hasan, M.; Guo, H.; Leichnitz, D.; Uzum, Z.; Richter, I.; Schalk, F.; Beemelmanns, C.; Hertweck, C.; Lackner, G.
    Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420 (2019), ACS Chem. Biol., 14, 2088-2094 .
    View publication on PubMed

Application

Application Comment Organism
synthesis the 3PG-F420 biosynthetic gene cluster is fully functional in Escherichia coli, enabling convenient production of the cofactor by fermentation Mycetohabitans rhizoxinica

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mycetohabitans rhizoxinica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-phospho-D-glycerate + GTP Mycetohabitans rhizoxinica
-
3-(D-glyceryl)-diphospho-5'-guanosine + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Mycetohabitans rhizoxinica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-phospho-D-glycerate + GTP
-
Mycetohabitans rhizoxinica 3-(D-glyceryl)-diphospho-5'-guanosine + diphosphate
-
?
additional information CofC from Paraburkholderia rhizoxinica accepts 3-phosphoglycerate (72.7%), 2-phospholactate (23.4%), and phosphoenolpyruvate (3.9%, reaction of EC 2.7.7.106) Mycetohabitans rhizoxinica ?
-
-

Synonyms

Synonyms Comment Organism
cofC
-
Mycetohabitans rhizoxinica
fbiD
-
Mycetohabitans rhizoxinica