Literature summary for 2.7.6.1 extracted from

Zhong, G.; Wei, W.; Guan, Q.; Ma, Z.; Wei, H.; Xu, X.; Zhang, S.; Lu, L.
Phosphoribosyl pyrophosphate synthetase, as a suppressor of the sepH mutation in Aspergillus nidulans, is required for the proper timing of septation (2012), Mol. Microbiol., 86, 894-907.

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Organism

Organism	UniProt	Comment	Textmining
Aspergillus nidulans	-	-	-
Aspergillus nidulans WJA01	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + D-ribose 5-phosphate	-	Aspergillus nidulans	AMP + 5-phospho-alpha-D-ribose 1-diphosphate	-	?
ATP + D-ribose 5-phosphate	-	Aspergillus nidulans WJA01	AMP + 5-phospho-alpha-D-ribose 1-diphosphate	-	?

Subunits

Subunits	Comment	Organism
heterodimer	-	Aspergillus nidulans

Synonyms

Synonyms	Comment	Organism
phosphoribosyl pyrophosphate synthetase	-	Aspergillus nidulans
PRPP synthetase	-	Aspergillus nidulans
PRS	-	Aspergillus nidulans

General Information

General Information	Comment	Organism
malfunction	the reduction of enzyme activity causes both premature and hyperseptation	Aspergillus nidulans
physiological function	normal cytokinesis is dependent on a normal level of enzyme activity. The enzyme is required for the proper timing of septation	Aspergillus nidulans

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Release 2023.1 (January 2023)