Literature summary for 2.7.4.6 extracted from

Kreimeyer, A.; Schneider, B.; Sarfati, R.; Faraj, A.; Sommadossi, J.P.; Veron, M.; Deville-Bonne, D.
NDP kinase reactivity towards 3TC nucleotides (2001), Antiviral Res., 50, 147-156.

Search for more literature for 2.7.4.6

Application

Application	Comment	Organism
medicine	low affinity of enzyme for L-dideoxynucleoside triphosphates, implications for antiviral therapies and treatment of AIDS	Dictyostelium discoideum

Organism

Organism	UniProt	Comment	Textmining
Dictyostelium discoideum	P22887	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	strong preference for D-enantiomers of antiviral nucleotide analogs like ddATP, ddCTP, 3'-deoxy-3'-thymidine, 2',3'-didehydro-2',3'-dideoxythymidine	Dictyostelium discoideum	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)