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Literature summary for 2.7.4.3 extracted from

  • Lange, P.R.; Geserick, C.; Tischendorf, G.; Zrenner, R.
    Functions of chloroplastic adenylate kinases in Arabidopsis (2008), Plant Physiol., 146, 492-504.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information T-DNA insertion mutant. Developing siliques of heterozygous parents contain approximately 25% pale and approximately 75% green seeds. Embryos dissected out of these seeds have a pale green to white color, whitish embryos are homozygous amk2 mutants. Homozygous amk2 seedlings are bleached and strongly retarded in growth. Amk2 heterozygous plants show significantly reduced expression of genes involved in purine de novo synthesis such as PurA, PurB, PurC, PurL, and PurM. Total adenylate kinase activity is reduced by 21% in for ATP formation and 37% for ADP formation Arabidopsis thaliana
additional information T-DNA insertion mutants show no phenotype, but significantly increased expression of genes involved in adenine salvage such as Apt1 to Apt5, and Adk1 and Adk2. Also, the PRS genes, responsible for supplying phosphoribosyl diphosphate are significantly induced. 2.5fold increase in expression of isoform Amk2 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Arabidopsis thaliana 9507
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chloroplast isoforms AMK2 and AMK5 Arabidopsis thaliana 9507
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cytosol isoforms AMK3 and AMK4 Arabidopsis thaliana 5829
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mitochondrion isofrms AMK21and AMK7 Arabidopsis thaliana 5739
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additional information isoforms AMK1 to AMK5 are much higher expressed than AMK6, while AMK7 is at the detection limit Arabidopsis thaliana
-
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Arabidopsis thaliana Q8VYL1 isoform Amk5
-
Arabidopsis thaliana Q9FIJ7 isoform Amk2
-