Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | a low molecular weight cofactor is required | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NEM | 10 mM, 64% inhibition | Bos taurus | |
PCMB | 0.5 mM, 79.5% inhibition | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.6 | - |
ATP | pH 7.4, 37°C | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | about 50% of the activation with Mg2+ | Bos taurus | |
Mg2+ | required | Bos taurus | |
Mn2+ | about 50% of the activation with Mg2+ | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | cortex | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thiamine diphosphate | - |
Bos taurus | ADP + thiamine triphosphate | - |
? | |
CTP + thiamine diphosphate | 6% of the activity with ATP | Bos taurus | CDP + thiamine triphosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
in Tris-HCl buffer slightly higher activity than in phosphate buffer | Bos taurus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Bos taurus | isoelectric focusing | - |
5.1 |