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Literature summary for 2.7.4.10 extracted from

  • Heppel, L.A.; Strominger, J.L.; Maxwell, E.S.
    Nucleoside monophosphate kinase, II. Transphosphorylation between adenosine monophophate and nucleoside triphosphates (1959), Biochim. Biophys. Acta, 32, 422-430.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement, 5-10 mM Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
calf
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.28
-
UTP Bos taurus

Storage Stability

Storage Stability Organism
-15°C, 3 years Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + AMP
-
Bos taurus 2 ADP
-
r
CTP + AMP
-
Bos taurus CDP + ADP
-
r
GTP + AMP not: CMP, GMP, IMP, UMP Bos taurus GDP + ADP
-
r
ITP + AMP no donor substrate is ribose 5'-triphosphate Bos taurus IDP + ADP
-
r
ITP + AMP not: GMP Bos taurus IDP + ADP
-
r
ITP + AMP not: IMP, CMP, UMP Bos taurus IDP + ADP
-
r
UTP + AMP
-
Bos taurus UDP + ADP
-
r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
in presence of ITP + AMP Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
6 9 half-maximal activity at pH 6 and pH 9 Bos taurus