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Literature summary for 2.7.4.1 extracted from

  • Gangaiah, D.; Kassem, I.I.; Liu, Z.; Rajashekara, G.
    Importance of polyphosphate kinase 1 for Campylobacter jejuni viable-but-nonculturable cell formation, natural transformation, and antimicrobial resistance (2009), Appl. Environ. Microbiol., 75, 7838-7849.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-
Campylobacter jejuni 81-176
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (phosphate)n
-
Campylobacter jejuni ADP + (phosphate)n+1
-
?
ATP + (phosphate)n
-
Campylobacter jejuni 81-176 ADP + (phosphate)n+1
-
?

Synonyms

Synonyms Comment Organism
poly-P kinase 1
-
Campylobacter jejuni
PPK1
-
Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
ATP
-
Campylobacter jejuni

General Information

General Information Comment Organism
malfunction ppk1-knockout mutant is deficient in poly-P accumulation, which is associated with a decreased ability to form viable-but-nonculturable cells under acid stress. The ppk1-deficient mutant shows a significant increase in susceptibility to erythromycin, cefotaxime, ciprofloxacin, rifampin, polymyxin B, tetracycline, cholic acid, taurocholic acid, deoxycholic acid, ethidium bromide, and SDS Campylobacter jejuni