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Literature summary for 2.7.2.7 extracted from

  • Diao, J.; Ma, Y.D.; Hasson, M.S.
    Open and closed conformations reveal induced fit movements in butyrate kinase 2 activation (2009), Proteins, 80, 1712.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, using 77 mM phosphate-citrate and 55% (w/v) PEG 200 Thermotoga maritima

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + butanoate Thermotoga maritima
-
ADP + butanoyl phosphate
-
?
ATP + isobutanoate Thermotoga maritima
-
ADP + isobutanoyl phosphate
-
?

Organism

Organism UniProt Comment Textmining
Thermotoga maritima Q9X278
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate precipitiation, heparin column chromatography, and Sephadex G25 gel filtration Thermotoga maritima

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + butanoate
-
Thermotoga maritima ADP + butanoyl phosphate
-
?
ATP + isobutanoate
-
Thermotoga maritima ADP + isobutanoyl phosphate
-
?

Subunits

Subunits Comment Organism
octamer x-ray crystallography Thermotoga maritima

Synonyms

Synonyms Comment Organism
Buk2
-
Thermotoga maritima
butyrate kinase 2
-
Thermotoga maritima

Cofactor

Cofactor Comment Organism Structure
ATP
-
Thermotoga maritima