Cloned (Comment) | Organism |
---|---|
DNA sequence determination and expression in Escherichia coli BL21(DE3) | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme acts as a disulfide reductase, e.g. plasmin reductase, in tumour angiogenesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme from Escherichia coli | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AsPC-1 cell | pancreatic carcinoma cell line, low amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
BT-20 cell | breast carcinoma cell line, reduced amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
BxPC-3 cell | pancreatic carcinoma cell line, low amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
HS-766T cell | pancreatic carcinoma cell line, the same amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
HS-766T cell | pancreatic carcinoma cell line, reduced amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
HT-1080 cell | - |
Homo sapiens | - |
Lim1215 cell | colon carcinoma cell line, nearly the same amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
Lim1863 cell | colon carcinoma cell line, increased amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
Lim2412 cell | colon carcinoma cell line, increased amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
MCF-7 cell | breast carcinoma cell line, the same amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
MDA-MB-231 cell | breast carcinoma cell line, low amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
SU.86.86 cell | pancreatic carcinoma cell line, very high amount of enzyme compared to HT-1080 cells | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 3-phospho-D-glycerate | - |
Homo sapiens | ADP + 1,3-diphosphoglycerate | - |
r | |
additional information | enzyme acts as a disulfide reductase, e.g. plasmin reductase, in tumour angiogenesis | Homo sapiens | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Homo sapiens | |
ATP | required as phosphate donor | Homo sapiens |