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Literature summary for 2.7.13.3 extracted from

  • Desikan, R.; Horak, J.; Chaban, C.; Mira-Rodado, V.; Witthoeft, J.; Elgass, K.; Grefen, C.; Cheung, M.K.; Meixner, A.J.; Hooley, R.; Neill, S.J.; Hancock, J.T.; Harter, K.
    The histidine kinase AHK5 integrates endogenous and environmental signals in Arabidopsis guard cells (2008), PLoS ONE, 3, e2491.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.13.3

Cloned(Commentary)

Cloned (Comment) Organism
gene ahk5, transient expression of GST-tagged full-length AHK5 in Arabidopsis thaliana protoplasts and Nicotiana benthamiana leaf cells the fusion protein in the cytoplasm, independent of whether the GFP tag is fused to the N-terminus or C-terminus of AHK5, expression profile of AHK5 in different tissues and cell types by semi-quantitative RT-PCR Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of ahk5 T-DNA insertion mutants, Arabidopsis mutants lacking AHK5 show reduced stomatal closure in response to H2O2, which is reversed by complementation with the wild type gene. Overexpression of AHK5 results in constitutively less stomatal closure. Abiotic stimuli that generate endogenous H2O2, such as darkness, nitric oxide and the phytohormone ethylene, also show reduced stomatal closure in the ahk5 mutants. However, ABA causes closure, dark adaptation induces H2O2 production and H2O2 induces NO synthesis in mutants, phenotype, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Arabidopsis thaliana 5737
-
cytosol
-
 Arabidopsis thaliana 5829
-
plasma membrane
-
 Arabidopsis thaliana 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana histidine kinases are part of two-component signal transduction systems that act to integrate environmental stimuli into a cellular response via a phosphotransfer relay mechanism, e.g. involved in stomatal guard cell response to H2O2, regulation of the physiological function, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information the enzyme performs regulatory autophosphorylation Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
guard cell
-
 Arabidopsis thaliana
-
guard cell expressed at low levels in guard cells Arabidopsis thaliana
-
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information histidine kinases are part of two-component signal transduction systems that act to integrate environmental stimuli into a cellular response via a phosphotransfer relay mechanism, e.g. involved in stomatal guard cell response to H2O2, regulation of the physiological function, overview Arabidopsis thaliana ?
-
 ?
additional information the enzyme performs regulatory autophosphorylation Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
AHK5
-
 Arabidopsis thaliana
hK5
-
 Arabidopsis thaliana
More AHK5 belongs to the the canonical HK class of proteins in Arabidopsis thaliana Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction Arabidopsis mutants lacking HK5 show reduced stomatal closure in response to H2O2, overexpression of HK5 results in constitutively less stomatal closure Arabidopsis thaliana
physiological function functional HK5 histidine kinase is required for H2O2 responses in stomatal guard cells Arabidopsis thaliana