Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of a cpkk1 knockout mutant, abnormal hyphae with a reduced number of septa and thinner cell walls are observed in DELTAcpkk1 mutant. The DELTAcpkk1 strain shows strong sensitivity to digestion and a low level of cell wall resistance. Phenotype, overview | Cryphonectria parasitica |
additional information | generation of a cpkk3 knockout mutant. Growth of DELTAcpkk3 is unaffected in either solid or liquid medium. Phenotype, overview | Cryphonectria parasitica |
additional information | generation of a DELTAcpkk2 knockout mutant showing a strong growth defect on solid media when compared with the control. Phenotype, overview | Cryphonectria parasitica |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Cryphonectria parasitica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cryphonectria parasitica | B2ZAW3 | gene cpkk2 | - |
Cryphonectria parasitica | B2ZAW3 | gene cpkk3 | - |
Cryphonectria parasitica | O93876 | gene cpkk1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypha | - |
Cryphonectria parasitica | - |
mycelium | no growth of wild-type and mutant strains at 8°C and 37°C | Cryphonectria parasitica | - |
Synonyms | Comment | Organism |
---|---|---|
cpkk1 | - |
Cryphonectria parasitica |
cpkk2 | - |
Cryphonectria parasitica |
cpkk3 | - |
Cryphonectria parasitica |
MAP2K | - |
Cryphonectria parasitica |
mitogen-activated protein kinase kinase | - |
Cryphonectria parasitica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Cryphonectria parasitica |
General Information | Comment | Organism |
---|---|---|
malfunction | virulence on chestnut and the developmental steps essential for mating are not affected in the DELTAcpkk3 strain. No alterations are reported in DELTAcpkk3, except under hyperosmotic conditions and in the presence of fludioxonil. Phenotype, overview | Cryphonectria parasitica |
malfunction | virulence on chestnut is affected in the DELTAcpkk1 strain which is also unable to complete the developmental steps essential for mating. Phenotype, overview | Cryphonectria parasitica |
malfunction | virulence on chestnut is affected in the DELTAcpkk2 strain which is also unable to complete the developmental steps essential for mating. DELTAcpkk2 mutants show higher sensitivity during growth in medium containing the antibiotic G418, i.e. geneticin. Phenotype, overview | Cryphonectria parasitica |
metabolism | Cpkk1, the Mkk1 orthologue, acts in a phosphorylation cascade essential for cell integrity | Cryphonectria parasitica |
metabolism | Cpkk2 is the Ste7 orthologue involved in the pheromone response pathway | Cryphonectria parasitica |
metabolism | Cpkk3 is the Pbs2 orthologue, the MAP2K activates during the high-osmolarity response | Cryphonectria parasitica |