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Literature summary for 2.7.12.2 extracted from

  • Cully, M.; Genevet, A.; Warne, P.; Treins, C.; Liu, T.; Bastien, J.; Baum, B.; Tapon, N.; Leevers, S.J.; Downward, J.
    A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1 (2010), Mol. Cell. Biol., 30, 481-495.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information stress-induced target of rapamycin complex 1 activation can be blocked by RNAi against mitogen-activated protein kinase kinase 3 and 6 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + p38
-
Homo sapiens ADP + phosphorylated p38
-
?

Synonyms

Synonyms Comment Organism
mitogen-activated protein kinase kinase 3
-
Homo sapiens
mitogen-activated protein kinase kinase 6
-
Homo sapiens
MKK3
-
Homo sapiens
MKK6
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens