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Literature summary for 2.7.12.1 extracted from

  • Poch, O.; Schwob, E.; de Fraipont, F.; Camasses, A.; Bordonne, R.; Martin, R.P.
    RPK1, an essential yeast protein kinase involved in the regulation of the onset of mitosis, shows homology to mammalian dual-specificity kinases (1994), Mol. Gen. Genet., 243, 641-653.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae may function in a checkpoint control which couples DNA replication to mitosis. The level of the RPK1 transcript is extremely low and constant throughout the mitotic cycle. However it is regulated during cellular differentiation, being decreased in alpha-factor-treated cells and increased late in meiosis in alpha diploids. Rpk1 is involved in a pathway that coordinates cell proliferation and differentiation ?
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P54199
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information may function in a checkpoint control which couples DNA replication to mitosis. The level of the RPK1 transcript is extremely low and constant throughout the mitotic cycle. However it is regulated during cellular differentiation, being decreased in alpha-factor-treated cells and increased late in meiosis in alpha diploids. Rpk1 is involved in a pathway that coordinates cell proliferation and differentiation Saccharomyces cerevisiae ?
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Synonyms

Synonyms Comment Organism
RPK1
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Saccharomyces cerevisiae
serine/threonine protein kinase MPS1
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Saccharomyces cerevisiae