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Literature summary for 2.7.11.7 extracted from

  • Yumura, S.; Yoshida, M.; Betapudi, V.; Licate, L.S.; Iwadate, Y.; Nagasaki, A.; Uyeda, T.Q.; Egelhoff, T.T.
    Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium (2005), Mol. Biol. Cell, 16, 4256-4266.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.7

Cloned(Commentary)

Cloned (Comment) Organism
expression of the 3 isozymes MHCK A, MHCK B, and MHCK C as GFP-fusion proteins Dictyostelium discoideum

Protein Variants

Protein Variants Comment Organism
additional information construction of single, double, and triple MHCK knockout cell lines concerning the 3 isozymes MHCK A, MHCK B, and MHCK C, the mutant cells defects in cytokinesis and myosin II overassembly increasing with the number of mutations, overview Dictyostelium discoideum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoskeleton
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 Dictyostelium discoideum 5856
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additional information the 3 isozymes MHCK A, MHCK B, and MHCK C show differential localization patterns in living cells, overview Dictyostelium discoideum
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Dictyostelium discoideum C-terminal phosphorylation of myosin heavy chain is required for regulation of myosin II filament assembly, the 3 isozymes MHCK A, MHCK B, and MHCK C show differential localization patterns in living cells ?
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 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
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 the 3 isozymes MHCK A, MHCK B, and MHCK C
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information C-terminal phosphorylation of myosin heavy chain is required for regulation of myosin II filament assembly, the 3 isozymes MHCK A, MHCK B, and MHCK C show differential localization patterns in living cells Dictyostelium discoideum ?
-
 ?

Subunits

Subunits Comment Organism
More MHCK domain organization Dictyostelium discoideum

Synonyms

Synonyms Comment Organism
myosin II heavy chain kinase
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 Dictyostelium discoideum