Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type and endoglin +/- mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
artery | - |
Mus musculus | - |
blood vessel | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
vascular endothelial cell | - |
Mus musculus | - |
vasculature | - |
Mus musculus | - |
vein | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
activin receptor-like-kinase 1 | - |
Mus musculus |
ACVRL1 | - |
Mus musculus |
ALK1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | in endoglin +/- mice, ACVRL1 is expressed in small regions of the distal arteries where endoglin is below detectable limits, co-expression of ACVRL1 and endoglin and associated pSmad1/5/8 signalling in the endothelial cells of distal arterioles | additional information |
General Information | Comment | Organism |
---|---|---|
malfunction | association of ACVRL1 mutations with a vascular disease, familial pulmonary artery hypertension | Mus musculus |
physiological function | activin receptor-like-kinase 1 is a receptor for ligands of the transforming growth factor-beta family | Mus musculus |