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BRENDA support

Literature summary for 2.7.11.26 extracted from

  • Dobocan, M.C.; Sadvakassova, G.; Congote, L.F.
    Chaperonin 10 as an endothelial-derived differentiation factor: role of glycogen synthase kinase-3 (2009), J. Cell. Physiol., 219, 470-476.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
GSK-3 inhibitor IX
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein 0.001 mg/ml chaperonin 10 stimulates the phosphorylation of GSK-3beta Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
K-562 cell
-
Homo sapiens
-
TF-1 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
glycogen synthase kinase-3beta
-
Homo sapiens
GSK-3beta
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens

General Information

General Information Comment Organism
physiological function GSK-3-regulated signal transduction pathways are important for stem cell maintenance and may be involved in events controlling cell differentiation Homo sapiens