Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.26 extracted from

  • Crespo-Biel, N.; Camins, A.; Gutierrez-Cuesta, J.; Melchiorri, D.; Nicoletti, F.; Pallas, M.; Canudas, A.M.
    Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model (2010), Hippocampus, 20, 962-970.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information the 3-nitropropionic acid treatment induces GSK-3beta truncation, calpeptin prevents GSK-3beta cleavage and cell death induced by 3-nitropropionic acid Mus musculus
SB-415286
-
Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein Akt phosphorylates GSK-3beta at serine residue 9 thereby inhibiting the activity of GSK-3beta, furthermore GSK-3beta is controlled by tyrosine phosphorylation, which increases its activity Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
Mus musculus
-

Synonyms

Synonyms Comment Organism
glycogen synthase kinase-3beta
-
Mus musculus
GSK-3beta
-
Mus musculus