Activating Compound | Comment | Organism | Structure |
---|---|---|---|
amyloid-beta 1-42 peptide | 0.005 mM | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dantrolene | in the presence of dantrolene, GSK-3beta activation and tau phosphorylation are decreased | Rattus norvegicus | |
GSK3betaI | 0.0001 mM | Rattus norvegicus | |
LiCl | 10 mM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortical neuron | - |
Rattus norvegicus | - |
primary culture | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tau | - |
Rattus norvegicus | ADP + protein tau phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glycogen synthase kinase-3beta | - |
Rattus norvegicus |
GSK-3beta | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |