Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ether | dramatic increase in the phosphorylation level of Ser9 of TPKI/GSK3beta immediately and 10 min after ether administration, followed by rapid virtual reversion to baseline by 20 min, no significant changes in the protein level or Tyr216 phosphorylation level of the enzyme | Mus musculus | |
additional information | cold water stress dramatically and transiently increases TPKI/GSK3beta phosphorylation at Ser9 accompanied by Akt phosphorylation | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inactivating phosphorylation of Ser9 of TPKI/GSK3beta in close correspondence with tau phosphorylation | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
male C57BL/6Njcl mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tau | - |
Mus musculus | ADP + protein tau phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TPKI/GSK3beta | - |
Mus musculus |