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Literature summary for 2.7.11.26 extracted from
- Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death (1999), FEBS Lett., 459, 421-426.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | - |
Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Butyrolactone | cdk5 inhibitor, isoenzyme TPKII | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + protein tau | Rattus norvegicus | - |
ADP + protein tau phosphate | - |
? | |
| ATP + protein tau | Rattus norvegicus Sprague-Dawley | - |
ADP + protein tau phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Sprague-Dawley | - |
| Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Rattus norvegicus | - |
| neuron | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + protein tau | - |
Rattus norvegicus | ADP + protein tau phosphate | - |
? | |
| ATP + protein tau | - |
Rattus norvegicus Sprague-Dawley | ADP + protein tau phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| tau protein kinase II system | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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