Activating Compound | Comment | Organism | Structure |
---|---|---|---|
tubulin | - |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | strongly inhibited by elevated concentrations of ATP uncomplexed with magnesium | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
isoenzyme TPKII, SDS-PAGE | Bos taurus |
45000 | - |
isoenzyme TPKI, SDS-PAGE | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tau | Bos taurus | - |
ADP + protein tau phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Purification (Comment) | Organism |
---|---|
2 isoenzymes, TPKI and TPKII | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.001 | - |
isoenzyme TPKI, optimum conditions | Bos taurus |
0.056 | - |
isoenzyme TPKI | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + alpha-casein | isoenzyme TPKI | Bos taurus | ADP + alpha-casein phosphate | - |
? | |
ATP + beta-casein | isoenzyme TPKII | Bos taurus | ADP + beta-casein phosphate | - |
? | |
ATP + histone H1 | isoenzyme TPKII | Bos taurus | ADP + histone H1 phosphate | - |
? | |
ATP + histone H2a | isoenzyme TPKII | Bos taurus | ADP + histone H2a phosphate | - |
? | |
ATP + histone H2b | isoenzyme TPKII | Bos taurus | ADP + histone H2b phosphate | - |
? | |
ATP + histone H3 | isoenzyme TPKII | Bos taurus | ADP + histone H3 phosphate | - |
? | |
ATP + MAP2 | isoenzyme TPKI and TPKII | Bos taurus | ADP + MAP2 phosphate | - |
? | |
ATP + protein tau | - |
Bos taurus | ADP + protein tau phosphate | - |
? | |
additional information | TPKI cannot phosphorylate K1, K2 and K3 peptides, histones H1, H2A, H2B and H3 and beta casein | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TPK | - |
Bos taurus |
TPKI | - |
Bos taurus |
TPKII | - |
Bos taurus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Bos taurus | isoenzyme TPKI, ? | - |
9.4 |