Activating Compound | Comment | Organism | Structure |
---|---|---|---|
H2O2 | activates, MEKK1 kinase activity and protein stability is regulated by H2O2 in a proteasome-dependent manner | Arabidopsis thaliana |
Application | Comment | Organism |
---|---|---|
additional information | MEKK1 regulates multiple processes during vegetative development, accumulation of reactive oxygen species and redox homeostasis | Arabidopsis thaliana |
Cloned (Comment) | Organism |
---|---|
expression of Myc-tagged MEKK1 under the 35 S cauliflower mosaic virus promoter in Arabidopsis protoplasts | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | MEKK1-deficient plants, are misregulated in the expression of a number of genes involved in cellular redox control and accumulate reactive oxygen species. Homozygous mekk1 mutant plants exhibit a lethal phenotype when developing true leaves. Mutant plants stay dwarfed and never reach maturity to produce seeds. Mekk1 and mpk4 mutant plants show similarities with respect to both, phenotype and H2O2 accumulation | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
protoplast | - |
Arabidopsis thaliana | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
Col-0 ecotype | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MPK4 | - |
Arabidopsis thaliana | ADP + phosphorylated MPK4 | - |
? | |
ATP + myelin basic protein | - |
Arabidopsis thaliana | ADP + phosphorylated myelin basic protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAPKKK | - |
Arabidopsis thaliana |
MEKK1 | - |
Arabidopsis thaliana |
mitogen-activated protein kinase kinase kinase | - |
Arabidopsis thaliana |