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Literature summary for 2.7.11.25 extracted from

  • Kicka, S.; Silar, P.
    PaASK1, a mitogen-activated protein kinase kinase kinase that controls cell degeneration and cell differentiation in Podospora anserina (2004), Genetics, 166, 1241-1252.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.25

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, overexpression of the enzyme can complement the defective mutant and results in increase crippled growth after infection Podospora anserina

Protein Variants

Protein Variants Comment Organism
additional information enzyme-defective mutant strains AS4-44 and AS6-5 are impaired in the development of crippled growth after infection causing a cell degenerative process, and are defective in mycelium pigmentation, aerial hyphae differentiation, and making of fruiting bodies showing female sterility, construction of mutants lacking the proline-riche region or the polyglutamine stretch, mutant phenotypes, overview Podospora anserina

Localization

Localization Comment Organism GeneOntology No. Textmining
protoplast
-
 Podospora anserina
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Podospora anserina the enzyme is involved in cell signaling and controls cell degeneration and cell differentiation and thus regulating development and pathogenicity sensing the external conditions ?
-
 ?

Organism

Organism UniProt Comment Textmining
Podospora anserina
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
 Podospora anserina
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in cell signaling and controls cell degeneration and cell differentiation and thus regulating development and pathogenicity sensing the external conditions Podospora anserina ?
-
 ?

Subunits

Subunits Comment Organism
More the large enzyme possesses several domains including a proline-rich region, indispensable for activity, and a 60-amino acid-long polyglutamine stretch, which is not necessary for full activity Podospora anserina

Synonyms

Synonyms Comment Organism
ASK1
-
 Podospora anserina
MAPKKK
-
 Podospora anserina
More the enzyme belongs to the MEK family Podospora anserina