Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | PD98059 | Rattus norvegicus | |
hypericin | hypericin-mediated inhibition of glutamate release appears to involve the suppression of mitogen-activated protein kinase pathway | Rattus norvegicus | |
U0126 | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
synaptosome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Rattus norvegicus | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
Rattus norvegicus | ADP + a phosphoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAP kinase | - |
Rattus norvegicus |
mitogen-activated kinase | - |
Rattus norvegicus |
mitogen-activated protein kinase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | the mitogen-activated protein kinase signaling pathway is one of the major second messenger systems regulating glutamate release at the presynaptic level | Rattus norvegicus |