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Literature summary for 2.7.11.24 extracted from

  • Rouse, J.; Cohen, P.; Trigon, S.; Morange, M.; Alonso-Llamazares, A.; Zamanillo, D.; Hunt, T.; Nebreda, A.R.
    A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins (1994), Cell, 78, 1027-1037.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme is activated in vitro by the p42 and p44 isoforms of MAPK, p42/p44MAPK Xenopus laevis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Xenopus laevis RKK, RK, and MAPKAP kinase-2 constitute a new stress-activated signal transduction pathway in vertebrates that is distinct from the classical MAPK cascade ?
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 ?

Organism

Organism UniProt Comment Textmining
Xenopus laevis P47812
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information RKK, RK, and MAPKAP kinase-2 constitute a new stress-activated signal transduction pathway in vertebrates that is distinct from the classical MAPK cascade Xenopus laevis ?
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 ?

Synonyms

Synonyms Comment Organism
MAPK-activated protein kinase-2
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 Xenopus laevis
MAPKAP kinase-2
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 Xenopus laevis
mitogen-activated protein kinase 2
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 Xenopus laevis