Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytokines | - |
Homo sapiens | |
MKK6 | activates | Homo sapiens | |
additional information | - |
Homo sapiens | |
additional information | when expressed in KB cells, SAPK4 is activated in response to cellular stresses and pro-inflammatory cytokines | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by the drugs SB 203580 and SB 202190 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O15264 | - |
- |
Homo sapiens | Q15759 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MAPKAP kinase-2 | - |
Homo sapiens | ADP + phosphorylated MAPKAP kinase-2 | - |
? | |
ATP + MAPKAP kinase-3 | - |
Homo sapiens | ADP + phosphorylated MAPKAP kinase-3 | - |
? | |
ATP + transcription factor ATF2 | - |
Homo sapiens | ADP + phosphorylated transcription factor ATF2 | - |
? | |
ATP + transcription factor Elk-1 | - |
Homo sapiens | ADP + phosphorylated transcription factor Elk-1 | - |
? | |
ATP + transcription factor SAP-1 | - |
Homo sapiens | ADP + phosphorylated transcription factor SAP-1 | - |
? | |
additional information | no phosphorylation of the activation domain of c-Jun | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mitogen-activated protein kinase 11 | - |
Homo sapiens |
mitogen-activated protein kinase 13 | - |
Homo sapiens |
stress-activated protein kinase-4 | - |
Homo sapiens |