Literature summary for 2.7.11.22 extracted from

Bonvini, P.; Zorzi, E.; Mussolin, L.; Monaco, G.; Pigazzi, M.; Basso, G.; Rosolen, A.
The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity (2009), Haematologica, 94, 944-955.

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Inhibitors

Inhibitors	Comment	Organism	Structure
flavopiridol	maximal inhibition at 24 h with doses of 200 nM or higher	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
anaplastic large cell lymphoma cell	-	Homo sapiens	-
FEPD cell	-	Homo sapiens	-
KARPAS-299 cell	-	Homo sapiens	-
SU-DHL-1 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + RNA polymerase II	-	Homo sapiens	ADP + phosphorylated RNA polymerase II	-	?

Synonyms

Synonyms	Comment	Organism
CDK2	-	Homo sapiens
CDK4	-	Homo sapiens
CDK9	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens
cyclin	-	Homo sapiens

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Release 2023.1 (January 2023)