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Literature summary for 2.7.11.22 extracted from

  • Lewis, A.E.; Rusten, M.; Hoivik, E.A.; Vikse, E.L.; Hansson, M.L.; Wallberg, A.E.; Bakke, M.
    Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7 (2008), Mol. Endocrinol., 22, 91-104.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.22

Protein Variants

Protein Variants Comment Organism
K41R catalytically inactive Homo sapiens
K41R catalytically inactive Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
roscovitine specific inhibitor of CDK1, CDK1, CDK5, CDK7, and CDK9 Homo sapiens
roscovitine specific inhibitor of CDK1, CDK1, CDK5, CDK7, and CDK9 Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens P50613
-
-
Mus musculus Q03147
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenocortical tumor cell
-
 Mus musculus
-
NCI-H295R cell
-
 Homo sapiens
-
Y-1 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + steroidogenic factor 1 also known as Ad4BP, systematic name NR5A1, the phosphorylation site is at Ser203 Homo sapiens ADP + phosphorylated steroidogenic factor 1
-
 ?
ATP + steroidogenic factor 1 also known as Ad4BP, systematic name NR5A1, the phosphorylation site is at Ser203 Mus musculus ADP + phosphorylated steroidogenic factor 1
-
 ?

Synonyms

Synonyms Comment Organism
cdk7
-
 Homo sapiens
cdk7
-
 Mus musculus
cyclin-dependent kinase 7 as part of the CDK-activating kinase complex, CDK7 is a component of the basal transcription factor TFIIH Homo sapiens
cyclin-dependent kinase 7 as part of the CDK-activating kinase complex, CDK7 is a component of the basal transcription factor TFIIH Mus musculus

Cofactor

Cofactor Comment Organism Structure
cyclin
-
 Homo sapiens
cyclin
-
 Mus musculus