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Literature summary for 2.7.11.22 extracted from
- Involvement of calpain and p25 of CDK5 pathway in ginsenoside Rb1s attenuation of beta-amyloid peptide25-35-induced tau hyperphosphorylation in cortical neurons (2008), Brain Res., 1200, 99-106.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| beta-amyloid peptide25-35 | - |
Rattus norvegicus | |
| ginsenoside Rb1 | attenuates beta-amyloid peptide25-35-induced CDK5 activation | Rattus norvegicus |  |
| p35 | - |
Rattus norvegicus | |
| p39 | - |
Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Rattus norvegicus | 5886 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebral cortical neuron | - |
Rattus norvegicus | - |
| primary culture | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + protein tau | - |
Rattus norvegicus | ADP + protein tau phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cdk5 | - |
Rattus norvegicus |
| cyclin-dependent kinase 5 | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Rattus norvegicus | |
| cyclin | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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