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Literature summary for 2.7.11.22 extracted from

  • Kesavapany, S.; Li, B.S.; Amin, N.; Zheng, Y.L.; Grant, P.; Pant, H.C.
    Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide (2004), Biochim. Biophys. Acta, 1697, 143-153.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information Cdk5 is activated by phosphorylation, integrin alpha1beta1 regulates phosphorylation of the axonal cytoskeleton protein Homo sapiens
p25 regulatory subunit and activator of Cdk5, soluble, p35 is cleaved to p25 by calpain leading to hyperactivation of Cdk5 Mus musculus
p25 regulatory subunit and activator of Cdk5, soluble, p35 is cleaved to p25 by calpain leading to hyperactivation of Cdk5 Homo sapiens
p35 regulatory subunit and activator of Cdk5 Rattus norvegicus
p35 regulatory subunit and activator of Cdk5 Sus scrofa
p35 regulatory subunit and activator of Cdk5 Canis lupus familiaris
p35 regulatory subunit and activator of Cdk5, membrane-bound, in neuronal growth cones, p35 is cleaved to p25 by calpain leading to hyperactivation of Cdk5 Mus musculus
p35 regulatory subunit and activator of Cdk5, membrane-bound, in neuronal growth cones, p35 is cleaved to p25 by calpain leading to hyperactivation of Cdk5 Homo sapiens
p39 regulatory subunit and activator of Cdk5 Mus musculus
p39 regulatory subunit and activator of Cdk5 Homo sapiens
p39 regulatory subunit and activator of Cdk5 Rattus norvegicus
p39 regulatory subunit and activator of Cdk5 Sus scrofa
p39 regulatory subunit and activator of Cdk5 Canis lupus familiaris

Cloned(Commentary)

Cloned (Comment) Organism
Cdk5, DNA sequence determination and analysis Drosophila melanogaster
Cdk5, DNA sequence determination and analysis Mus musculus
Cdk5, DNA sequence determination and analysis Rattus norvegicus
Cdk5, DNA sequence determination and analysis Sus scrofa
Cdk5, DNA sequence determination and analysis Saccharomyces cerevisiae
Cdk5, DNA sequence determination and analysis Canis lupus familiaris
Cdk5, DNA sequence determination and analysis Caenorhabditis elegans
Cdk5, DNA sequence determination and analysis Doryteuthis pealeii
Cdk5, DNA sequence determination and analysis Danio rerio
Cdk5, DNA sequence determination and analysis, co-expression of Cdk5 and p35 in HEK293 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information construction of Cdk5-knockout mutant mice that are embryonically lethal with very few viable at birth dying a few hours postpartum, p35 and p39 double-knockout mutant mice show a similar phenotype, the KO mice show higher ERK1/2 activity and increased neurofilament phosphorylation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
additional information integrin alpha1beta1 regulates phosphorylation of the axonal cytoskeleton protein, development of inhibitory peptides Homo sapiens
roscovitine
-
Caenorhabditis elegans
roscovitine
-
Canis lupus familiaris
roscovitine
-
Danio rerio
roscovitine
-
Doryteuthis pealeii
roscovitine
-
Drosophila melanogaster
roscovitine Cdk5 inhibition induces neurotransmitter release in vivo Homo sapiens
roscovitine
-
Mus musculus
roscovitine
-
Rattus norvegicus
roscovitine
-
Saccharomyces cerevisiae
roscovitine
-
Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-
cytoskeleton neuronal Drosophila melanogaster 5856
-
cytoskeleton neuronal Mus musculus 5856
-
cytoskeleton neuronal Homo sapiens 5856
-
cytoskeleton neuronal Rattus norvegicus 5856
-
cytoskeleton neuronal Sus scrofa 5856
-
cytoskeleton neuronal Canis lupus familiaris 5856
-
cytoskeleton neuronal Caenorhabditis elegans 5856
-
cytoskeleton neuronal Doryteuthis pealeii 5856
-
cytoskeleton neuronal Danio rerio 5856
-
Golgi apparatus
-
Homo sapiens 5794
-
synapse
-
Homo sapiens 45202
-
synaptosome
-
Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Canis lupus familiaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + axonal cytoskeleton protein Homo sapiens regulated by integrin alpha1beta1 ADP + phosphorylated axonal cytoskeleton protein
-
?
ATP + c-Jun N-terminal kinase 3 Mus musculus i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 Homo sapiens i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 Rattus norvegicus i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 Sus scrofa i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 Canis lupus familiaris i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 Doryteuthis pealeii i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + Cprk Homo sapiens i.e. Cdk5/p35-regulated kinase ADP + phosphorylated Cprk
-
?
ATP + dephosphin Homo sapiens Cdk5 regulates endocytosis involving dephosphin activity, overview ADP + phosphorylated dephosphin
-
?
ATP + ErbB2 Mus musculus phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin ADP + phosphorylated ErbB2
-
?
ATP + ErbB2 Homo sapiens phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin ADP + phosphorylated ErbB2
-
?
ATP + ErbB3 Mus musculus phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin ADP + phosphorylated ErbB3
-
?
ATP + ErbB3 Homo sapiens phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin ADP + phosphorylated ErbB3
-
?
ATP + MEK1 Mus musculus Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + MEK1 Homo sapiens Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + MEK1 Rattus norvegicus Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + MEK1 Sus scrofa Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + MEK1 Canis lupus familiaris Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + MEK1 Doryteuthis pealeii Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview ADP + phosphorylated MEK1
-
?
ATP + Munc-18 Homo sapiens involved in regulation of exocytosis involving SNARE proteins, Munc-18 is required for mediating secretory responsesoverview ADP + phosphorylated Munc-18
-
?
ATP + NF-H Mus musculus neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-H Homo sapiens neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-H Sus scrofa neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-H Rattus norvegicus neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-H Canis lupus familiaris neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-H Doryteuthis pealeii neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-H
-
?
ATP + NF-M Mus musculus neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NF-M Homo sapiens neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NF-M Rattus norvegicus neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NF-M Sus scrofa neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NF-M Canis lupus familiaris neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NF-M Doryteuthis pealeii neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein ADP + phosphorylated NF-M
-
?
ATP + NR1 receptor Homo sapiens involved in synaptic transmission, overview ADP + phosphorylated NR1 receptor
-
?
ATP + NR2 receptor Homo sapiens involved in synaptic transmission, phosphorylation of Ser1232 on the A subunit upregulates NMCAR activity, overview ADP + phosphorylated NR2 receptor
-
?
ATP + tau protein Mus musculus hyperactivated Cdk5-p25 ADP + phosphorylated tau protein
-
?
ATP + tau protein Homo sapiens hyperactivated Cdk5-p25 ADP + phosphorylated tau protein
-
?
ATP + VGCC Homo sapiens a voltage-dependent calcium channel, phosphorylation within the intracellular loop of the channel inhibiting interaction with SNARE proteins, SNAP-25, and synaptotagmin I required for neurotransmitter release, overview ADP + phosphorylated NR1 receptor
-
?
additional information Drosophila melanogaster Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins ?
-
?
additional information Caenorhabditis elegans Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins ?
-
?
additional information Danio rerio Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins ?
-
?
additional information Mus musculus Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, and is critical for neuronal survival, deregulation of Cdk5 occurs in neurodegeneration ?
-
?
additional information Rattus norvegicus Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration ?
-
?
additional information Sus scrofa Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration ?
-
?
additional information Canis lupus familiaris Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration ?
-
?
additional information Doryteuthis pealeii Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration ?
-
?
additional information Homo sapiens Cdk5 regulation, overview, Cdk5 regulates endocytosis through association with amphiphysin and dynamin, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration ?
-
?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
-
-
Canis lupus familiaris
-
-
-
Danio rerio
-
zebrafish
-
Doryteuthis pealeii
-
common squid
-
Drosophila melanogaster
-
-
-
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein Cdk5 is regulated by reversible phosphorylation Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
brain
-
Homo sapiens
-
brain
-
Rattus norvegicus
-
brain
-
Sus scrofa
-
brain
-
Canis lupus familiaris
-
cerebellum
-
Homo sapiens
-
cerebral cortex
-
Mus musculus
-
nervous system
-
Drosophila melanogaster
-
nervous system
-
Mus musculus
-
nervous system
-
Homo sapiens
-
nervous system
-
Sus scrofa
-
nervous system
-
Canis lupus familiaris
-
nervous system
-
Caenorhabditis elegans
-
nervous system
-
Doryteuthis pealeii
-
nervous system
-
Danio rerio
-
neuroblastoma cell
-
Homo sapiens
-
neuron
-
Drosophila melanogaster
-
neuron
-
Mus musculus
-
neuron
-
Homo sapiens
-
neuron
-
Rattus norvegicus
-
neuron
-
Sus scrofa
-
neuron
-
Canis lupus familiaris
-
neuron
-
Caenorhabditis elegans
-
neuron
-
Doryteuthis pealeii
-
neuron
-
Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + axonal cytoskeleton protein
-
Homo sapiens ADP + phosphorylated axonal cytoskeleton protein
-
?
ATP + axonal cytoskeleton protein regulated by integrin alpha1beta1 Homo sapiens ADP + phosphorylated axonal cytoskeleton protein
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Mus musculus ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Homo sapiens ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Rattus norvegicus ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Sus scrofa ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Canis lupus familiaris ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation inhibits JNK3 and leads to reduced phosphorylation of c-jun and to reduced apoptosis Doryteuthis pealeii ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Mus musculus ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Homo sapiens ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Rattus norvegicus ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Sus scrofa ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Canis lupus familiaris ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + c-Jun N-terminal kinase 3 i.e. JNK3, phosphorylation at Thr131 Doryteuthis pealeii ADP + phosphorylated c-Jun N-terminal kinase 3
-
?
ATP + Cprk i.e. Cdk5/p35-regulated kinase Homo sapiens ADP + phosphorylated Cprk
-
?
ATP + dephosphin
-
Homo sapiens ADP + phosphorylated dephosphin
-
?
ATP + dephosphin Cdk5 regulates endocytosis involving dephosphin activity, overview Homo sapiens ADP + phosphorylated dephosphin
-
?
ATP + ErbB2 phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin Mus musculus ADP + phosphorylated ErbB2
-
?
ATP + ErbB2 phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin Homo sapiens ADP + phosphorylated ErbB2
-
?
ATP + ErbB2 phosphorylation at Thr871 Mus musculus ADP + phosphorylated ErbB2
-
?
ATP + ErbB2 phosphorylation at Thr871 Homo sapiens ADP + phosphorylated ErbB2
-
?
ATP + ErbB3 phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin Mus musculus ADP + phosphorylated ErbB3
-
?
ATP + ErbB3 phosphorylation of the neuregulin receptor by Cdk5 is involved in regulation of neuregulin Homo sapiens ADP + phosphorylated ErbB3
-
?
ATP + ErbB3 phosphorylation at Ser1120 Mus musculus ADP + phosphorylated ErbB3
-
?
ATP + ErbB3 phosphorylation at Ser1120 Homo sapiens ADP + phosphorylated ErbB3
-
?
ATP + MEK1
-
Homo sapiens ADP + phosphorylated MEK1
-
?
ATP + MEK1
-
Rattus norvegicus ADP + phosphorylated MEK1
-
?
ATP + MEK1
-
Sus scrofa ADP + phosphorylated MEK1
-
?
ATP + MEK1
-
Canis lupus familiaris ADP + phosphorylated MEK1
-
?
ATP + MEK1
-
Doryteuthis pealeii ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Mus musculus ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Homo sapiens ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Rattus norvegicus ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Sus scrofa ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Canis lupus familiaris ADP + phosphorylated MEK1
-
?
ATP + MEK1 Cdk5 regulates the ERK1/2 pathway through phosphorylation of MEK1, overview Doryteuthis pealeii ADP + phosphorylated MEK1
-
?
ATP + MEK1 phosphorylation at Thr286 Mus musculus ADP + phosphorylated MEK1
-
?
ATP + Munc-18
-
Homo sapiens ADP + phosphorylated Munc-18
-
?
ATP + Munc-18 involved in regulation of exocytosis involving SNARE proteins, Munc-18 is required for mediating secretory responsesoverview Homo sapiens ADP + phosphorylated Munc-18
-
?
ATP + NF-H neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Mus musculus ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Homo sapiens ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein that correlates neurit outgrowth, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Sus scrofa ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Rattus norvegicus ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Canis lupus familiaris ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Doryteuthis pealeii ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats Mus musculus ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats Rattus norvegicus ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats Sus scrofa ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats Canis lupus familiaris ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats Doryteuthis pealeii ADP + phosphorylated NF-H
-
?
ATP + NF-H neurofilament protein, phosphorylation at the KSP repeats, hyperactivated Cdk5-p25 Homo sapiens ADP + phosphorylated NF-H
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Mus musculus ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Homo sapiens ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Rattus norvegicus ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Sus scrofa ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Canis lupus familiaris ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, regulated by the myelin-associate glycoprotein Doryteuthis pealeii ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats Mus musculus ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats Rattus norvegicus ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats Sus scrofa ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats Canis lupus familiaris ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats Doryteuthis pealeii ADP + phosphorylated NF-M
-
?
ATP + NF-M neurofilament protein, phosphorylation at the KSP repeats, hyperactivated Cdk5-p25 Homo sapiens ADP + phosphorylated NF-M
-
?
ATP + NR1 receptor
-
Homo sapiens ADP + phosphorylated NR1 receptor
-
?
ATP + NR1 receptor involved in synaptic transmission, overview Homo sapiens ADP + phosphorylated NR1 receptor
-
?
ATP + NR2 receptor involved in synaptic transmission, phosphorylation of Ser1232 on the A subunit upregulates NMCAR activity, overview Homo sapiens ADP + phosphorylated NR2 receptor
-
?
ATP + NR2 receptor with phosphorylation sites on both, A and B subunits, e.g. Ser1232 on the A subunit Homo sapiens ADP + phosphorylated NR2 receptor
-
?
ATP + tau protein hyperactivated Cdk5-p25 Mus musculus ADP + phosphorylated tau protein
-
?
ATP + tau protein hyperactivated Cdk5-p25 Homo sapiens ADP + phosphorylated tau protein
-
?
ATP + VGCC a voltage-dependent calcium channel, phosphorylation within the intracellular loop of the channel inhibiting interaction with SNARE proteins, SNAP-25, and synaptotagmin I required for neurotransmitter release, overview Homo sapiens ADP + phosphorylated NR1 receptor
-
?
ATP + VGCC a voltage-dependent calcium channel, phosphorylation within the intracellular loop of the channel Homo sapiens ADP + phosphorylated NR1 receptor
-
?
additional information Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins Drosophila melanogaster ?
-
?
additional information Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins Caenorhabditis elegans ?
-
?
additional information Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins Danio rerio ?
-
?
additional information Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, and is critical for neuronal survival, deregulation of Cdk5 occurs in neurodegeneration Mus musculus ?
-
?
additional information Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration Rattus norvegicus ?
-
?
additional information Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration Sus scrofa ?
-
?
additional information Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration Canis lupus familiaris ?
-
?
additional information Cdk5 regulation, overview, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration Doryteuthis pealeii ?
-
?
additional information Cdk5 regulation, overview, Cdk5 regulates endocytosis through association with amphiphysin and dynamin, Cdk5 is involved in neuronal migration and phosphorylation of neurofilaments and cytoskeletal proteins, deregulation of Cdk5 occurs in neurodegeneration Homo sapiens ?
-
?
additional information Cdk5 associates with amphiphysin and dynamin Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
Cdk5
-
Drosophila melanogaster
Cdk5
-
Mus musculus
Cdk5
-
Homo sapiens
Cdk5
-
Rattus norvegicus
Cdk5
-
Sus scrofa
Cdk5
-
Saccharomyces cerevisiae
Cdk5
-
Canis lupus familiaris
Cdk5
-
Caenorhabditis elegans
Cdk5
-
Doryteuthis pealeii
Cdk5
-
Danio rerio

Cofactor

Cofactor Comment Organism Structure
ATP
-
Drosophila melanogaster
ATP
-
Mus musculus
ATP
-
Homo sapiens
ATP
-
Rattus norvegicus
ATP
-
Sus scrofa
ATP
-
Saccharomyces cerevisiae
ATP
-
Canis lupus familiaris
ATP
-
Caenorhabditis elegans
ATP
-
Doryteuthis pealeii
ATP
-
Danio rerio