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Literature summary for 2.7.11.22 extracted from

  • De Bondt, H.L.; Rosenblatt, J.; Jancarik, J.; Jones, H.D.; Morgan, D.O.; Kim, S.H.
    Crystal structure of cyclin-dependent kinase 2 (1993), Nature, 363, 595-602.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structures of the human CDK2 apoenzyme and its Mg2+ ATP complex, determined to 2.4 A resolution. The structure is bi-lobate, but contains a unique helix-loop segment that interferes with ATP and protein substrate binding and probably plays a key part in the regulation of all cyclin-dependent kinases Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P24941
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Synonyms

Synonyms Comment Organism
cell division protein kinase 2
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Homo sapiens