Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.21 extracted from

  • Xiang, Y.; Takeo, S.; Florens, L.; Hughes, S.E.; Huo, L.J.; Gilliland, W.D.; Swanson, S.K.; Teeter, K.; Schwartz, J.W.; Washburn, M.P.; Jaspersen, S.L.; Hawley, R.S.
    The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle (2007), PLoS Biol., 5, e323.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.21

Cloned(Commentary)

Cloned (Comment) Organism
the polo fragment is cloned into pBluescript and subcloned into the pUASP vector to generate transgenic flies Drosophila melanogaster

Inhibitors

Inhibitors Comment Organism Structure
matrimony the matrimony protein acts as a negative regulator of polo during the later stages of G2 arrest during meiosis Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
centromere
-
 Drosophila melanogaster
-
-
chromosome
-
 Drosophila melanogaster 5694
-
nucleus
-
 Drosophila melanogaster 5634
-
spindle
-
 Drosophila melanogaster 5819
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein Drosophila melanogaster
-
 ADP + phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster P52304
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cystocyte
-
 Drosophila melanogaster
-
germarium
-
 Drosophila melanogaster
-
oocyte
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Cdc25
-
 Drosophila melanogaster ADP + phosphorylated Cdc25
-
 ?
ATP + protein
-
 Drosophila melanogaster ADP + phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
Polo kinase
-
 Drosophila melanogaster