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Literature summary for 2.7.11.20 extracted from

  • Ayada, K.; Yokota, K.; Kawahara, Y.; Yamamoto, Y.; Hirai, K.; Inaba, T.; Kita, M.; Okada, H.; Yamamoto, K.; Oguma, K.
    Immune reactions against elongation factor 2 kinase: specific pathogenesis of gastric ulcer from Helicobacter pylori infection (2009), Clin. Dev. Immunol., 2009, 850623.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
using an EasyXpress Linear Template kit Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
extracted from gastric epithelial cells, determined by SDS-PAGE and Western blot analysis Homo sapiens
100000
-
recombinant protein, determined by SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [elongation factor 2] Homo sapiens
-
ADP + [elongation factor 2] phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens O00418
-
-

Purification (Commentary)

Purification (Comment) Organism
with a nickel column by affinity chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HGC-27 cell gastric epithelial cell Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [elongation factor 2]
-
Homo sapiens ADP + [elongation factor 2] phosphate
-
?

Synonyms

Synonyms Comment Organism
EF-2K
-
Homo sapiens
elongation factor 2 kinase
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens over-expressed by a stressful, heat-stressed, environment, Helicobacter pylori infection enhances the EF-2K expression in HGC-27 cells as much as heat stress do up