Literature summary for 2.7.11.2 extracted from

Fereidoonnezhad, M.; Faghih, Z.; Mojaddami, A.; Sakhteman, A.; Rezaei, Z.
A comparative docking studies of dichloroacetate analogues on four isozymes of pyruvate dehydrogenase kinase in humans (2016), Indian J. Pharm. Edu. Res., 50, S32-S38.

No PubMed abstract available

Search for more literature for 2.7.11.2

Inhibitors

Inhibitors	Comment	Organism	Structure
Dichloroacetate	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)]	Homo sapiens	-	ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q15118	-	-
Homo sapiens	Q15119	-	-
Homo sapiens	Q15120	-	-
Homo sapiens	Q16654	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)]	-	Homo sapiens	ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PDK1	isoform	Homo sapiens
PDK2	isoform	Homo sapiens
PDK3	isoform	Homo sapiens
PDK4	isoform	Homo sapiens
pyruvate dehydrogenase kinase	-	Homo sapiens

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Release 2023.1 (January 2023)