Literature summary for 2.7.11.18 extracted from

Herring, B.P.; El-Mounayri, O.; Gallagher, P.J.; Yin, F.; Zhou, J.
Regulation of and telokin expression in smooth muscle tissues (2006), Am. J. Physiol., 291, C817-C827.

Search for more literature for 2.7.11.18

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	myocardin, a cardiac SAP, SAF-A/B, acinus, PIAS, domain-containing protein, is important in regulation of enzyme expression, overview, induction of enzyme expression by the thyrotroph embryonic factor binding to the the CArG box of the promoter, TEF	Mus musculus

Cloned(Commentary)

Cloned (Comment)	Organism
gene mylk1, located on chromosome 16, contains at least 31 exons, DNA and amino acid sequence determination and analysis, genetic structure and regulation, the serum response factor myocardin plays a central role in regulating mylk1 gene expression, a highly conserved CArG element within 130-kDa MLCK intron 1 is important for promoter activity binding activation factors like myocardin, homebox proteins, GATA family members, and the thyrotroph embryonic factor, regulation model, overview	Mus musculus

Cloned (Comment)

Organism

gene mylk1, located on chromosome 16, contains at least 31 exons, DNA and amino acid sequence determination and analysis, genetic structure and regulation, the serum response factor myocardin plays a central role in regulating mylk1 gene expression, a highly conserved CArG element within 130-kDa MLCK intron 1 is important for promoter activity binding activation factors like myocardin, homebox proteins, GATA family members, and the thyrotroph embryonic factor, regulation model, overview

Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	regulation of the MLCK promoters and gene expression involving myocardin, model, overview	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	gene mylk1, encoding two isozymes: the endothelial, long or nonmuscle 220-kDa MLCK and a short, smooth muscle 130-kDa MLCK	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	two isozymes: the endothelial, long or nonmuscle 220-kDa MLCK and a short, smooth muscle 130-kDa MLCK, mechanism of regulation of tissue-specific mylk gene expression, overview	Mus musculus	-
smooth muscle	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	regulation of the MLCK promoters and gene expression involving myocardin, model, overview	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
myosin light chain kinase	-	Mus musculus