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Literature summary for 2.7.11.18 extracted from

  • Kigoshi, T.; Uchida, K.; Kaneko, M.; Iwasaki, R.; Nakano, S.; Azukizawa, S.; Morimoto, S.
    Direct inhibition of smooth muscle myosin light chain kinase by arachidonic acid in a purified system (1990), Biochem. Biophys. Res. Commun., 171, 369-374.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
arachidonic acid
-
Meleagris gallopavo
linoleic acid
-
Meleagris gallopavo
additional information no inhibition by diacylglycerol, phosphatidylserine Meleagris gallopavo
oleic acid
-
Meleagris gallopavo
unsaturated fatty acids irreversible by Ca2+/calmodulin Meleagris gallopavo

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Meleagris gallopavo

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin light chain Meleagris gallopavo
-
ADP + myosin light chain phosphate
-
?

Organism

Organism UniProt Comment Textmining
Meleagris gallopavo
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gizzard
-
Meleagris gallopavo
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin light chain
-
Meleagris gallopavo ADP + myosin light chain phosphate
-
?
ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Meleagris gallopavo ADP + myosin light chain phosphate
-
?

Cofactor

Cofactor Comment Organism Structure
Calmodulin requirement Meleagris gallopavo