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Literature summary for 2.7.11.18 extracted from
- Bovine stomach myosin light chain kinase: purification, characterization, and comparison with the turkey gizzard enzyme (1982), Biochemistry, 21, 6890-6896.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cAMP-dependent protein kinase | phosphorylates light chain myosin kinase leading to decreased affinity from calmodulin | Bos taurus | |
| cAMP-dependent protein kinase | phosphorylates light chain myosin kinase leading to decreased affinity from calmodulin | Meleagris gallopavo | |
| EGTA | - |
Bos taurus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| myofibril | associated | Gallus gallus | 30016 | - |
| myofibril | associated | Meleagris gallopavo | 30016 | - |
| myofibril | associated | Bos taurus | 30016 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Gallus gallus | |
| Ca2+ | - |
Meleagris gallopavo | |
| Ca2+ | - |
Bos taurus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Gallus gallus |
| additional information | - |
- |
Meleagris gallopavo |
| additional information | - |
- |
Bos taurus |
| 130000 | - |
1 * 130000, SDS-PAGE | Meleagris gallopavo |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + myosin light chain | Gallus gallus | - |
ADP + myosin light chain phosphate | - |
? | |
| ATP + myosin light chain | Meleagris gallopavo | - |
ADP + myosin light chain phosphate | - |
? | |
| ATP + myosin light chain | Bos taurus | - |
ADP + myosin light chain phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Gallus gallus | - |
- |
- |
| Meleagris gallopavo | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Meleagris gallopavo |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gizzard | - |
Gallus gallus | - |
| gizzard | - |
Meleagris gallopavo | - |
| rumen | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 6.1 | 8.7 | - |
Meleagris gallopavo |
| 8.1 | 8.9 | - |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + myosin light chain | - |
Gallus gallus | ADP + myosin light chain phosphate | - |
? | |
| ATP + myosin light chain | - |
Meleagris gallopavo | ADP + myosin light chain phosphate | - |
? | |
| ATP + myosin light chain | - |
Bos taurus | ADP + myosin light chain phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Gallus gallus |
| monomer | - |
Bos taurus |
| monomer | 1 * 130000, SDS-PAGE | Meleagris gallopavo |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Calmodulin | requirement | Gallus gallus | |
| Calmodulin | requirement | Meleagris gallopavo | |
| Calmodulin | requirement | Bos taurus | |
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Release 2023.1 (January 2023)
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